Welcome to the Walczak Lab

Cell, Molecular and Cancer Biology Program

Genome, Cell and Developmental Biology Program

Biochemistry Graduate Program 

Biotechnology MS Program

• Susan Kline-Smith, PhD in Anatomy and Cell Biology (CEO Susan Chang Consulting, LLC)
• Kathleen Hertzer, MD/PhD in Anatomy and Cell Biology (Surgeon, Placerville California)
• Ke Wang, MS. in Molecular Cell and Developmental Biology (Scientist at Genzyme)
• Xin Zhang, PhD in Molecular Cell and Developmental Biology (Asst. Professor Chinese Academy of Sciences)
• David Hedrick, MD/MS in Anatomy and Cell Biology (Physician, Indianapolis)
• Rania Rizk, PhD in Molecular Cell and Developmental Biology (Instructor, RC Med Review, LLC)
• Shang Cai, PhD in Biochemistry (Faculty Position at the Westlake Institute of Advanced Study, Hangzhou, China)
• PK Moua, PhD in Molecular Cell and Developmental Biology, (Lecturer at Beloit College)
• Amber Yount, PhD in Biochemistry (Asst. Professor at Franklin College)
• Lesley Weaver, PhD in Molecular Cell and Developmental Biology, (Post-doc at Johns Hopkins School of Public Health)
• Sathiya Dharmaiah, MS in Molecular and Cellular Biochemistry (Research associate at Leidos Biomedical Research)
• Hailing Zong, PhD in Molecular Cell and Developmental Biology, (Scientist, Advanced Cell Diagnostics)
• Tirzah Brown, MS in Anatomy and Cell Biology Education, (Faculty Fellow, Ivy Tech Community College)
• Stefan Husted, MS in Pharmacology, (Study Design Leader at Covance)
• Shengyao Chen, PhD in Molecular Cell and Developmental Biology, (Bioinformatics Scientist III at IDT)
• Jeanna Wigley, MS in Biotechnology, (Research Associate at Indiana University)
• Jared Ross, MS in Biotechnology, (PhD student at Indiana University)
• Mark Hazelbaker, MS in Biotechnology (PhD student at UNC-Chapel Hill)

• Chris Sontag, PhD Biochemistry (Research associate at IU)

• Suzannah Park, BS Biology (MD, IU School of Medicine)
• Thomas Lipkin, BS Biology (PhD, Columbia University)
• Jennifer Luckki, BS Biology
• Emmanuel Obeng, BS Biology
• Kevin Bohannon, BS Biology (PhD, Northwestern University)
• Jenna Devare, BS Biochemistry (MD, Cornell Medical School)
• Ellen Weinzapful, BS Biology (PhD, University of Pennsylvania)
• Lesley Weaver, BS Biology (PhD, Indiana University, Post-doc Johns Hopkins School of Public Health)
• Sarah Hainline, BS Biology (PhD, Vanderbilt University; Clinical Data Manager at Sarah Cannon Research Institute)
• Laura Wetzel, BS Biochemistry (PhD student at UC-Berkeley)
• David Hsieh, BS Biology
• Robby Pease, BS Biology
• Caitlin Dunn, BS Biology (MD/PhD student at University of Cincinnati)
• Stephanie Lamb, BS Biology (PhD, Vanderbilt University; Microbiology Fellow, University of Washington)
• Arpita Appannagari, BS Biology (MS, Columbia University School of Public Health)
• Eric Workman, BS Biochemistry (transferred to Yale University)
• Stefan Husted, BS Biochemistry/Neuroscience (MS at Indiana University; Genetic Toxicologist, Covance)
• Sachin Jain, BS Biology (Medical student at Indiana University)
• Christina Moe, BS Biology (Medical student at The Ohio State University)
• Sarina Rodriguez, BS Biology (Research scientist at Eli Lilly)
• Sarah Yde, BS Biology (PhD student at University of Chicago)
• Lauren Frank, BS Biology (MS Genetic Counseling)
• Stephanie Zhang, BS Biology, BS Environmental and Sustainability Studies, Intern at Hoosier Action
• Jason Zhang, BS Human Biology, Medical Student at Marian University

• Eugene C. Gan, (PhD Duke University)
• Jane Stout, (Bloomington Drosophila Stock Center)
• Sarah Johnstone, (PhD MIT)
• Chantal LeBlanc, (Research Associate Yale University)
• Jay Pilrose, (Cook Pharmica)
   

• Zong, H., Hazelbaker, M., Moe, C., Ems-McClung, S.C. Hu, K., and Walczak, C.E. (2021) Spatial Regulation of MCAK Promotes Cell Polarization and Focal Adhesion Turnover to Drive Robust Cell Migration. Mol. Biol. Cell 32: 590-604 doi: 10.1091/mbc.E20-05-0301.
• Walker, B.C, Walczak, C.E. and Cochran, J.C. (2021) Switch-1 Instability at the Active Site Decopules ATP Hydrolysis from Force Generation in Myosin II. Cytoskeleton. 78(1):3-13. doi: 10.1002/cm.21650.
• Ems-McClung, S.C, Emch, M., Zhang, S., Mahnoor, S., Weaver, L.N. and Walczak, C.E. (2020). RanGTP Induces an Effector Gradient of XCTK2 and Importin alpha/beta for Spindle Microtubule Cross-linking. J. Cell Biol. 219: doi: 10.1083/jcb.201906045
• Ems-McClung, SC and Walczak, CE. (2020). In Vitro FRET- and Fluorescence-Based Assays to Study Protein Conformation and Protein-Protein Interactions in Mitosis. Methods Mol. Biol. 2101: 93-122. doi: 10.1007/978-1-0716-0219-5_7.
• Hartsough, KE and Walczak, CE (2019).  Cell Division: Tailoring a Swiftly Scaling Spindle.  Curr. Biol. 29: R1135-1137.
• Rotelli, M., Policastro, R.A., Boling, A., Killion, A., Weinberg, A., Dixon, M., Zentner, G.E., Walczak, C.E., Lilly, M.A., and Calvi, B.R., (2019). A Cyclin A-Myb-MuvB-Aurora B network regulates the choice between mitotic cycles and polyploid endoreplication cycles.PLOS Genetics. Jul 10;15(7):e1008253. doi: 10.1371
• Shrestha, S., Hazelbaker, M., Yount, A.L. and Walczak, C.E. (2018). Emerging Insights into the Function of Kinesin-8 Proteins in Microtubule Length Regulation. Biomolecules. 9(1).  Doi/10.3390/biom9010001
• Fürthauer, S., Lemma, B., Foster, P.J., Ems-McClung, S.C., Walczak, C.E., Dogic, Z., Needleman, D.J., and Shelley, M.J. (2019). Self-straining of actively crosslinked microtubule networks. Nature Physics.  15:1295-1300. doi.org/10.1038/s41567-019-0642-1
• Huang, Y., Li, T., Ems-McClung, S.C., Walczak, C.E., Prigent, C., Xueliang, Z., Zhang, X., and Zheng, Y. (2018). Aurora A Activation in Mitosis is Promoted by BuGZ. J. Cell Biol. 217: 107-116.
• Walczak, C.E., Zong, H., Jain, S., and Stout, J.R. (2016). Spatial Regulation of Astral Microtubule Dynamics by Kif18B. Mol. Biol. Cell. 27: 3021-3030.
• Chen, S., Stout, J.R., Dharmaiah, S., Yde, S., Calvi, B.R., and Walczak, C.E. (2016). Transient Endoreplication Down-Regulates the Kinesin-14 HSET and Contributes to High Levels of Genomic Instability. Mol. Biol. Cell. 27: 2911-2923.
• Zong, H., Carnes, S.K., Moe, C., Walczak, C.E., and Ems-McClung, S.C. (2016). The Far C-terminus of MCAK Regulates its Conformation and Pole focusing. Mol. Biol. Cell. 27: 1451-1464.
• Pannu, V., Rida, P.C.G, Ogden, A., Pawar, S., Bowen, N.J., Cheng, A., Rudd, K., Gupta, M.V., Oprea-Ilies, O., Walczak, C.E., Cantuaria, C., and Aneja, R. (2015). Overexpression of Human Kinesin-14 family motor HSET Fuels Tumor Progression and Predicts Poor Clinical Outcomes in Breast Cancer Patients. Oncotarget. 6:6076-6091.
• Weaver, L.N. and Walczak, C.E. (2015). Spatial Gradients Controlling Spindle Assembly. Biochem. Soc. Trans. 43: 7-12.
• Weaver, L.N., Ems-McClung, S.C., Chen, S.R., Yang, G., Shaw, S.L., and Walczak, C.E. (2015). The Ran-GTP Gradient Spatially Regulates XCTK2 Activity in the Spindle. Curr. Biol. 25: 1509-1514.
• Yount, A.L, Zong, H., and Walczak, C.E. (2015). Regulatory Mechanisms that Control Mitotic Kinesins. Exp. Cell Res. 15:70-77.
• Verhey, K.J., Cochran, J.C., and Walczak, C.E. (2015). The Kinesin Superfamily in “Kinesins and Cancer”, Frank Kozielski, editor. Humana Press. 1-25.
• Ems-McClung, S.C., Hainline, S.G., Devare, J., Zong, H., Cai, S. Carnes, S., Shaw, S.L., and Walczak, C.E. (2013). Aurora B Regulates MCAK Activity Through a Phospho-conformational Switch that Reduces MCAK Association. Curr. Biol. 23:2491-2499.
• Walczak, C.E., Gayek, S., and Ohi, R. (2013) Microtubule Depolymerizing Kinesins. Annu. Rev. Cell Dev. Biol. 219:417-441.
• Huang, R., Oh, H., Arrendale, A., Martin, V.A., Galan, J. Workman, E.J., Stout, J.R., Walczak, C.E., Tao, W.A., Borch, R.F., Geahlen, R.L. (2013). Intracellular Targets for a Phosphotyrosine Peptidomimetic Include the Mitotic Kinesin, MCAK. Biochem Pharmacol. 86:597-611.
• Earnshaw, W.C….. Walczak, C. E…….. (2013). Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 21:101-106.